Worldwide, the goal of clinical research is to develop knowledge that improves human health or augments understanding of human biology.In biomedical research, two CARB SMART BREAD pillars have been identified - informed consent and independent review by an Ethics Committee.Informed consent is a consent given by a competent individual, who is willin
Metastatic Ductal Eccrine Adenocarcinoma with Excellent Response to Immunotherapy
Eccrine carcinoma, a subtype of which is ductal eccrine adenocarcinoma (DEA), is a rare cutaneous malignancy.For metastatic eccrine carcinoma, there are very limited data to guide treatment.Conventional chemotherapy is of limited benefit and there is only a small body of evidence for the use of immunotherapy in non-DEA eccrine carcinomas.We report
PERUBAHAN WILAYAH LAUT ZONA EKONOMI EKSLUSIF RUSIA DI LAUT HITAM PASCA ANEKSASI KRIMEA
Rusia merupakan negara yang memiliki wilayah yang sangat luas dan sumber daya yang banyak.Februari 2014 Rusia melakukan aksi aneksasi di Semenanjung Krimea.Konsekuensi anekasi Krimea oleh Rusia melampaui kekhawatiran akan kedaulatan tanah Barware dan jauh ke perairan Laut Hitam terutama yang berhubungan dengan laut Zona Ekonomi Eksklusif.Pada Zona
Vascular traffic control of neutrophil recruitment to the liver by microbiota-endothelium crosstalk
Summary: During bloodstream infections, neutrophils Beginner home to the liver as part of an intravascular immune response to eradicate blood-borne pathogens, but the mechanisms regulating this crucial response are unknown.Using in vivo imaging of neutrophil trafficking in germ-free and gnotobiotic mice, we demonstrate that the intestinal microbiot
Radiosensitizing effects of pyrogallol-loaded mesoporous or-ganosilica nanoparticles on gastric cancer by amplified ferroptosis
Radiotherapy (RT) incorporated multidisciplinary treatment is producing excellent clinical results, but its efficacy in treating late-stage gastric cancer is constrained by radioresistance and RT-related toxicity.Especially, since reactive oxygen species are the pivotal effectual molecules of ionizing radiation, improving ROS production by Humidity